Saturday, November 7, 2009

Drug Research and Technology updates

Here are some drug research updates from my reading-

Trichostatin A may prevent premature labor -

Trichostatin A, a cancer treatment, "may prevent premature labour," according to researchers from Newcastle University publication. They tested "trichostatin A on tissue taken from 36 women undergoing a caesarean," finding "an average 46 percent reduction in contractions for the spontaneously contracting tissue and an average 54 percent reduction in the oxytocin induced contractions."

Study indicates basal insulin regimen may be better for some patients with type 2 diabetes-

An online publication dated Oct. 22 in the New England Journal of Medicine indicates that "patients with type 2 diabetes who require insulin on top of oral therapy to control glycated hemoglobin may do better if they start on a basal insulin versus biphasic insulin or prandial insulin."

According to a study published online in the Journal Endocrinology, reports are that a study in mice population suggests that resveratrol "may help the body fend off type 2 diabetes".

Is Liraglutide a better tool for weight loss than other obesity drugs ?

In a study published online in The Lancet, it has been published that "In the fight against obesity, the investigational diabetes drug liraglutide (Victoza) may be a better tool than some weight loss drugs, even for patients who don't have diabetes, researchers said". "In a clinical trial, more than 75 percent of obese nondiabetic patients on a high three-mg dose of the glucagon-like peptide-1 (GLP-1) analogue lost more than five percent of their body weight," while "30 percent of those on placebo lost that much, and just 44 percent of those on orlistat (Alli, Xenical)," researchers said.

Do incidences of roravirus infection potentially seem to decrease with vaccinations ?

According to data published in the CDC's Morbidity and Mortality Weekly Report ,"Since routine vaccination of infants against rotavirus started in the United States in 2006, there's been a substantial reduction in the number of cases of rotavirus disease in children. Before 2006, rotavirus caused 20 to 60 deaths each year in the United States, along with 55,000 to 70,000 hospitalizations, 205,000 to 272,000 emergency department visits, and 410,000 outpatient visits among children younger than five." Yet, an "analysis of data from a national network of sentinel laboratories showed that the 2007-2008 and 2008-2009 rotavirus seasons were both shorter and began later than pre-vaccine seasons (2000 to 2006)."

Disclaimer : The above information is for dissemination of knowledge only and should not be construed as medical advise. The scientific data presented here has been studied from leading publications already in public domain. The author however, assumes no responsibility regarding trueness of the data. Reference to stated journals and websites is encouraged in case of additional interest.

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